The University of Toronto’s Terrence Donnelly Center for Cellular and Biomolecular Research (TDCCBR) is Canada’s foremost human genome research center. The facility is home to 400 specialists who perform ground-breaking research in genetics and disease. Organized as a collaborative, interdisciplinary research center, TDCCBR required a facility that was functional, highly flexible, and technologically advanced. Located at the southeast corner of the University of Toronto’s St. George campus, the 248,378-square-foot, $86 million USD/$100 million Canadian facility is in the center of the city’s densely built historic district. Formerly a small parking and service area, the narrow building site is straddled between two historic buildings on College Street, a main city thoroughfare. TDCCBR is both a symbolic and physical connection that bridges the academic community to the north, the medical community to the south, and people who live and work in the area.
